Endocrine and Metabolic

25 free practice questions shared by students. Answer them right here — no account needed.

Practise theseOne at a time, in a random order, with the explanation after each.

A 31-year-old woman presents with six months of fatigue, nausea and 7 kg of weight loss. She has been adding extra salt to everything and craves potato chips. F…

Clinical rotations · common

A 38-year-old woman presents with three weeks of aching pain in the front of her neck that worsens when she turns her head or swallows and radiates up to both e…

Clinical rotations · middle twist

A 46-year-old woman has a body mass index of 32 kg/m² and treated hypertension. Her mother developed type 2 diabetes at 58 years of age. She has no polyuria, po…

Clinical rotations · middle twist

A 24-year-old woman with type 1 diabetes presents with abdominal pain, vomiting and deep breathing. Her blood glucose concentration is 24 mmol/L, venous pH is 7…

Clinical rotations · middle twist

A 76-year-old woman taking denosumab for osteoporosis develops pain around a mandibular molar and undergoes extraction. Twelve weeks later, a segment of hard ti…

Clinical rotations · common

A 45-year-old man attends a health assessment. He has a sedentary occupation, a waist circumference of 108 cm and a first-degree relative with type 2 diabetes,…

Clinical rotations · middle twist

A 28-year-old man with type 1 diabetes uses a continuous subcutaneous insulin infusion. He develops nausea after the pump gives an occlusion alarm; his blood gl…

Clinical rotations · common

A 31-year-old woman with type 1 diabetes is being treated for diabetic ketoacidosis with intravenous insulin and 0.9% sodium chloride. Four hours later, her blo…

Clinical rotations · common

A 24-year-old man with type 1 diabetes presents with vomiting and abdominal pain. His blood glucose concentration is 28 mmol/L, blood ketones are 6.4 mmol/L and…

Clinical rotations · middle twist

A 34-year-old woman taking carbimazole for Graves disease presents with fever, malaise and two painful oral ulcers. She has a temperature of 38.7°C and mild cer…

Clinical rotations · common

A 58-year-old man with primary adrenal insufficiency is scheduled for multiple dental extractions under general anaesthesia. He takes hydrocortisone 20 mg in th…

Clinical rotations · common

A 46-year-old woman taking prednisolone 7.5 mg each morning for polymyalgia rheumatica requires extraction of one mobile premolar. She is otherwise well, has ta…

Clinical rotations · middle twist

A 38-year-old woman presents with two weeks of pain in the front of her neck radiating to her jaw, together with palpitations, sweating and 2 kg of weight loss.…

Clinical rotations · common

A 64-year-old man with type 2 diabetes has an HbA1c of 62 mmol/mol (7.8%) despite maximal-dose metformin and attention to diet and activity. He had a myocardial…

Clinical rotations · middle twist

A 52-year-old man has a blood pressure of 162/98 mmHg despite adequate doses of perindopril, amlodipine and hydrochlorothiazide, with good adherence confirmed.…

Clinical rotations · middle twist

A 34-year-old woman with known autoimmune Addison disease presents with vomiting, abdominal pain and profound weakness. Her blood pressure is 82/48 mmHg, sodium…

Clinical rotations · common

A 29-year-old man has progressive bone pain, proximal weakness and two atraumatic metatarsal fractures. Serum phosphate is 0.44 mmol/L (0.80–1.50), calcium is 2…

Clinical rotations · niche

A 63-year-old woman reports several months of bone pain and difficulty climbing stairs. She has no focal neurological deficit. Serum calcium is 2.19 mmol/L (2.1…

Clinical rotations · common

A 48-year-old woman has a slowly enlarging thyroid nodule, intermittent diarrhoea and facial flushing. Her TSH is 1.6 mIU/L (0.4–4.0), and serum calcitonin is 1…

Clinical rotations · common

A 61-year-old man has a 1.5-cm thyroid nodule with a solid markedly hypoechoic appearance, irregular margins and punctate echogenic foci on ultrasound. His TSH…

Clinical rotations · common