Year 4

28 free practice questions shared by students. Answer them right here — no account needed.

Practise theseOne at a time, in a random order, with the explanation after each.

A 54-year-old man with no family history of prostate cancer attends his GP for a routine check-up. He is asymptomatic and has no significant past medical histor…

Clinical rotations · middle twist

A 58-year-old man with no symptoms attends your clinic for a general health check. He is concerned because his uncle and cousin both died of pancreatic cancer.…

Clinical rotations · middle twist

A 60-year-old man with a history of chronic diarrhea presents with muscle weakness and lethargy. Laboratory tests show: potassium 3.1 mmol/L (3.5-5.0 mmol/L), b…

Clinical rotations · middle twist

A 64-year-old man presents with a right-sided groin bulge that becomes more prominent on coughing. He reports no pain and has no difficulty with daily activitie…

Clinical rotations · middle twist

A 62-year-old man presents with a bulge in his right groin that becomes more prominent when he coughs and reduces spontaneously when lying down. On examination,…

Foundations · middle twist

A 54-year-old man presents with persistent heartburn and regurgitation despite six weeks of once-daily omeprazole. He has no dysphagia, weight loss, or anemia.…

Clinical rotations · middle twist

A 72-year-old woman is undergoing evaluation for persistent postprandial fullness and intermittent epigastric discomfort. She has no history of reflux or dyspha…

Clinical rotations · middle twist

A 58-year-old man with a 3-year history of gastroesophageal reflux disease (GERD) undergoes an upper endoscopy for ongoing reflux symptoms. Endoscopy reveals a…

Clinical rotations · middle twist

A 68-year-old man presents to his general practitioner for a routine review of his medications. He has a history of osteoarthritis, for which he takes naproxen…

Clinical rotations · middle twist

A 76-year-old man presents to the emergency department with a 6-hour history of passing large volumes of bright red blood per rectum. He feels lightheaded and f…

Clinical rotations · middle twist

A 68-year-old man presents to the emergency department with a 24-hour history of worsening abdominal pain, nausea, and vomiting. He has a history of open sigmoi…

Clinical rotations · middle twist

A 72-year-old man with a history of hypertension and heart failure with reduced ejection fraction (HFrEF) presents the emergency department due to sudden onset…

Clinical rotations · middle twist

A 5-day-old newborn presents with purulent conjunctivitis, eyelid swelling, and significant eye discharge. What is the most appropriate initial treatment?

Clinical rotations · middle twist

A 45-year-old woman is brought to the emergency room after developing diffuse skin tenderness and blistering. Her symptoms initially started with fever and mala…

Pre-internship · middle twist

A 72-year-old man with Alzheimer’s disease is brought to the emergency room by his daughter due to confusion and lethargy over the past few days. His daughter s…

Pre-internship · middle twist

A 24-year-old woman presents with right knee pain, swelling, and difficulty walking for the past 2 days. She also reports multiple joint pains and swelling. The…

Clinical rotations · middle twist

A 72-year-old male with history of stage 4 chronic kidney disease presents to the clinic after suffering from increasing fatigability and pallor. · Hemoglobin:…

Clinical rotations · middle twist

During an epidemiological study of a population of 100,500 people, 500 individuals were identified as existing cases of a certain disease. Over the course of on…

Mechanisms of disease · middle twist

A 59-year-old male presents to the emergency room after he develops a fever of 38.5°C (101.3°F). He was recently diagnosed with leukemia and started chemotherap…

Pre-internship · middle twist

A 20-year-old college student presents to the emergency department with a fever, severe headache, and neck stiffness for the past 12 hours. One of his roommates…

Pre-internship · middle twist