Pharmacology

A 70 kg man requires debridement and suturing of an 18 cm laceration on his forearm in the emergency department. There is no adrenaline-containing local anaesth…

Emergency and Toxicology · Mechanisms of disease · common

A 22-year-old woman is brought from a music festival by paramedics. She is agitated and confused, her temperature is 39.8 °C, pulse 132/min, blood pressure 158/…

Emergency and Toxicology · Clinical rotations · middle twist

A 67-year-old man with alcohol dependence has mild withdrawal 10 hours after his last drink, with anxiety, tremor and nausea but no hallucinations or seizure. H…

Gastroenterology and Hepatology · Mechanisms of disease · middle twist

A 59-year-old woman develops sharp central chest pain two days after an uncomplicated ST-elevation myocardial infarction. She says it is worse when she takes a…

Cardiovascular · Mechanisms of disease · middle twist

A 46-year-old woman with bipolar disorder has been stable on lithium carbonate for five years. She presents with two days of nausea, vomiting and unsteadiness o…

Psychiatry and Mental Health · Clinical rotations · common

A 52-year-old male is currently an inpatient on a hospital ward. He developed rapid-onset swelling of the lips and face during his hospital stay. He reports no…

Year 4 · Pre-internship · common

Which mechanism explains how antidepressants (e.g., amitriptyline, duloxetine) provide pain relief?

Year 4 · Clinical rotations · common

What is the primary mechanism of action of ketamine in pain management?

Year 4 · Clinical rotations · common

A 25-year-old patient receiving acetylcysteine for immediate-release paracetamol poisoning develops a rash, urticaria, and flushing shortly after the infusion s…

Curtin CAT · Mechanisms of disease · middle twist