Every question
The whole community bank, newest first. 1,426 questions.
A 35-year-old woman at 31 weeks’ gestation has six weeks of low mood, guilt and early-morning waking. During the past week she has stopped eating, believes her…
Psychiatry and Mental Health · Clinical rotations · common
A 27-year-old man with no previous psychiatric history is brought to hospital by his family after two weeks of little sleep, expansive business plans and increa…
Psychiatry and Mental Health · Clinical rotations · common
A 38-year-old woman with bipolar disorder started haloperidol 10 days ago for a manic episode. She now reports that she cannot sit still, repeatedly walks aroun…
Psychiatry and Mental Health · Clinical rotations · middle twist
A 46-year-old man with recurrent major depression tells his general practitioner that he intends to take all his prescribed medicines after his partner leaves f…
Psychiatry and Mental Health · Pre-internship · common
A 32-year-old woman at 10 weeks’ gestation presents with four days of almost no sleep, excessive spending and increasingly intrusive plans to start several busi…
Obstetrics and Gynaecology · Clinical rotations · middle twist
A 29-year-old man with schizophrenia is brought to the emergency department after threatening another patient. He is pacing, shouting and clenching his fists; h…
Psychiatry and Mental Health · Pre-internship · common
A 23-year-old man has recurrent episodes of muscle cramps during intense exercise. During an episode, plasma lactate rises from 1.2 to 1.5 mmol/L (reference 0.5…
Biomedical Science · Foundations · middle twist
A 54-year-old woman has progressive exertional dyspnoea. Spirometry shows a forced expiratory volume in one second of 2.4 L (reference greater than 2.0 L) and a…
Biomedical Science · Mechanisms of disease · middle twist
A laboratory technician is found unconscious in a poorly ventilated garage. Arterial blood shows pH 7.39, PaO2 13.0 kPa (reference 10.7–13.3 kPa), and PaCO2 5.1…
Biomedical Science · Mechanisms of disease · common
A 68-year-old man develops sudden pleuritic chest pain and tachypnoea after prolonged immobility. Arterial blood gas analysis on room air shows pH 7.48, PaCO2 3…
Biomedical Science · Mechanisms of disease · common
A patient with profuse watery diarrhoea caused by enterotoxin receives an oral solution containing sodium and glucose. Before treatment, stool output is high an…
Biomedical Science · Foundations · common
A 7-month-old infant becomes lethargic after an overnight fast during gastroenteritis. Blood glucose is 1.9 mmol/L (reference 3.5–6.0 mmol/L), beta-hydroxybutyr…
Biomedical Science · Foundations · niche
An enzyme catalyses conversion of substrate S to product P. Without inhibitor, Vmax is 120 μmol/min and the Michaelis constant is 4 mmol/L. In the presence of i…
Biomedical Science · Foundations · common
A 35-year-old woman has palpitations and a 9 kg weight loss over 3 months. Her free thyroxine is 48 pmol/L (reference 10–22 pmol/L), TSH is less than 0.01 mIU/L…
Biomedical Science · Mechanisms of disease · common
A 41-year-old woman has progressive weight gain, proximal muscle weakness and easy bruising. Her 24-hour urinary free cortisol is 780 nmol/day (reference less t…
Biomedical Science · Mechanisms of disease · middle twist
A 29-year-old woman has a plasma bicarbonate concentration of 15 mmol/L (reference 22–29 mmol/L) and a normal anion gap. Her urine pH is 6.2 during bicarbonate…
Biomedical Science · Mechanisms of disease · middle twist
A healthy adult receives an intravenous glucose load. Plasma glucose is 12 mmol/L (reference 3.5–7.8 mmol/L), the measured glomerular filtration rate is 120 mL/…
Biomedical Science · Mechanisms of disease · common
A 48-year-old woman has a new holosystolic murmur and exertional dyspnoea. Echocardiography shows a regurgitant volume from the left ventricle into the left atr…
Biomedical Science · Mechanisms of disease · common
A 62-year-old man undergoes left ventricular pressure-volume loop analysis during cardiac catheterisation. Before an intervention, his end-diastolic volume is 1…
Biomedical Science · Mechanisms of disease · common
A 24-year-old woman with type 1 diabetes on a basal-bolus insulin regimen is an inpatient awaiting elective surgery scheduled for the afternoon. Mid-morning she…
Nursing · Clinical rotations · common