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A 34-year-old woman who is breastfeeding at four weeks after birth requests contraception. She has migraine with visual aura and reports that her periods were p…

Obstetrics and Gynaecology · Clinical rotations · common

A 29-year-old woman requests emergency contraception four days after unprotected intercourse. She has a body mass index of 34 kg/m² and takes carbamazepine for…

Obstetrics and Gynaecology · Mechanisms of disease · middle twist

A 38-year-old woman presents with two days of very heavy bleeding during an otherwise predictable menstrual cycle. Her blood pressure is 118/72 mmHg, she is not…

Obstetrics and Gynaecology · Clinical rotations · common

A 42-year-old man was treated with radioactive iodine for Graves disease three days ago. He now reports dry mouth and painful swelling in front of both ears, wo…

Geriatrics and Palliative Care · Clinical rotations · common

A 34-year-old woman taking carbimazole for Graves disease presents with fever, malaise and two painful oral ulcers. She has a temperature of 38.7°C and mild cer…

Endocrine and Metabolic · Clinical rotations · common

A 49-year-old woman with a recently diagnosed adrenal pheochromocytoma requires drainage of a painful dental abscess before definitive tumour surgery. Her blood…

Emergency and Toxicology · Clinical rotations · niche

A 58-year-old man with primary adrenal insufficiency is scheduled for multiple dental extractions under general anaesthesia. He takes hydrocortisone 20 mg in th…

Endocrine and Metabolic · Clinical rotations · common

A 46-year-old woman taking prednisolone 7.5 mg each morning for polymyalgia rheumatica requires extraction of one mobile premolar. She is otherwise well, has ta…

Endocrine and Metabolic · Clinical rotations · middle twist

A 46-year-old woman presents with fatigue, jaundice and dark urine that began after a respiratory infection. She has mild splenomegaly but no renal or neurologi…

AMC · Clinical rotations · common

A 35-year-old woman presents with bruising, gum bleeding and increasing lethargy. Her haemoglobin is 84 g/L (115–155), platelet count 18 × 10^9/L (150–400), whi…

AMC · Clinical rotations · middle twist

A 27-year-old woman has painless enlargement of the left side of her neck and drenching night sweats. She has no sore throat, dental symptoms or recent travel.…

AMC · Clinical rotations · common

A 29-year-old man presents with fever, bruising and aching in the long bones. He has pallor, scattered petechiae and a spleen palpable 2 cm below the costal mar…

AMC · Clinical rotations · middle twist

A 74-year-old man reports several months of fatigue and burning of his feet. He has a smooth, sore tongue and impaired vibration sense at both ankles. His haemo…

AMC · Clinical rotations · common

A 20-year-old university student with bipolar disorder is admitted voluntarily during a manic episode. She has capacity and agrees that her sister may be told t…

Ethics and Professional Practice · Pre-internship · common

A 56-year-old man with severe depression has decision-making capacity and agrees that electroconvulsive therapy may be appropriate. Before signing consent, he a…

Ethics and Professional Practice · Pre-internship · common

A 34-year-old man with major depression tells his general practitioner that he has thought about dying and has imagined taking an overdose. He has no tablets at…

Ethics and Professional Practice · Pre-internship · common

A 42-year-old woman with recurrent bipolar disorder has made a written advance statement saying that she would want lithium during a future manic relapse. She i…

Ethics and Professional Practice · Pre-internship · middle twist

A 29-year-old woman with type 1 diabetes refuses her evening insulin after becoming convinced that the injections are being used to poison her. She can repeat t…

Ethics and Professional Practice · Pre-internship · common

A 31-year-old woman at 9 weeks of pregnancy presents with vaginal bleeding and cramping after passing several clots. Her pulse is 88 beats/minute, blood pressur…

Obstetrics and Gynaecology · Clinical rotations · middle twist

A 34-year-old woman is reviewed after treatment with single-dose intramuscular methotrexate for a confirmed, unruptured tubal ectopic pregnancy. She remains wel…

Obstetrics and Gynaecology · Clinical rotations · middle twist