A 45-year-old woman presents because a mole on her calf has become darker and larger over three months. It is 8 mm across with an irregular edge and several shades of brown and black, and dermatoscopy shows an atypical pigment network. She is otherwise well, and there are no palpable regional lymph nodes. Which one of the following is the most appropriate next step?
Keep going — a set of ten like this one, one at a time.
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